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Nature Materials 3, 355 - 356 (2004)
doi:10.1038/nmat1143

Nanopores: Flossing with DNA

John J. Kasianowicz1

  1. John J. Kasianowicz is at the National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA. e-mail: john.kasianowicz@nist.gov


Passing a DNA strand many times back-and-forth through a protein nanopore would enable the interaction between them to be studied more closely. This may now be possible, using a dumbbell-shaped DNA–polymer complex, which may lead to a more reliable analysis of DNA sequences using nanopores.

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