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Morphogenesis

Laying down the tracks

Nature Materials volume 11, pages 490–492 (2012)Cite this article

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To drive the formation of tubular structures, cells remodel their extracellular microenvironment to induce coordinated migration. It is now found that a mechanical feedback loop, involving the interaction of cell traction forces with collagen fibres, facilitates the formation of long epithelial tubules.

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Figure 1: Collective cell migration and tubule formation.

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Authors and Affiliations

  1. Christopher C. DuFort and Valerie M. Weaver are at the Department of Surgery, Luke Cassereau, University of California San Francisco, San Francisco, California 94143-0456, USA,

    Luke Cassereau, Christopher C. DuFort & Valerie M. Weaver

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  1. Luke Cassereau
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  2. Christopher C. DuFort
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  3. Valerie M. Weaver
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Correspondence to Valerie M. Weaver.

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Cassereau, L., DuFort, C. & Weaver, V. Laying down the tracks. Nature Mater 11, 490–492 (2012). https://doi.org/10.1038/nmat3345

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