Heparan sulfate and viral tropism   p 1177
Tomas Bergström¹, Edward Trybala¹ & Dorothe Spillmann²


 
VEGF-nitric oxide reciprocal regulation  p 1177
Aldona Dembinska-Kiec¹, Jozef Dulak¹, Lakasz Partyka¹, Igor Huk² & Tadeusz Mailnski³


 
news

 
Women in trials: Clinical hold or stranglehold?  p 1179



 
The UK endorses DIY genetic screening  p 1180



 
Satcher a safe bet for Surgeon General  p 1181



 
"Innovation" in AIDS vaccines  p 1181



 
New lease on life for aging research  p 1182



 
Indian Contract research -- economic necessity or sellout?  p 1182



 
AMA aims for ethical high road following Sunbeam disaster  p 1183



 
Cancer researchers travel to China  p 1183



 
$34 million neuropeptide deal   p 1183



 
Repeated transfusion for sickle cell  p 1184



 
Commercial interest in cord blood escalates  p 1184



 
Italy encourages return of research scientists  p 1184



 
commentary

 
Philanthropic goals  p 1185
Bridget M. Ogilvie


 
news & views

 
NF-kappaB and bone: The breaking point  p 1189
Yousef Abu-Amer & M. Mehrdad Tondravi



 
A green light for virulence gene expression  p 1190
Eduardo A. Groisman



 
To oxidize or not to oxidize?  p 1192
Michael B. Kastan



 
TNF inhibition and sepsis -- sounding a cautionary note  p 1193
Georges E. Grau & Daniela N. Maennel



 
Healing hormones  p 1195
John Rømer^1,2 Leif R. Lund¹ & Keld Danø¹



 
The ABCs of AMD  p 1196
Gabriel H. Travis¹ & Jean Bennett²



 
The end replication problem: More than one solution  p 1198
Victoria Lundblad



 
Dimers are a girl's best friend  p 1199
Sarah Rowland-Jones



 
Polyglutamines, nuclear inclusions and neurodegeneration  p 1201
Astrid Lunkes & Jean-Louis Mandel



 
commentary & review

 
Quantitative angiogenesis assays: Progress and problems  p 1203
Rakesh K. Jain¹, Karlheinz Schlenger², Michael Höckel² & Fan Yuan³


 
articles

 
Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels  p 1209
Gillian S. Ashcroft^1,2, Joanne Dodsworth¹, Egon van Boxtel², Roy W. Tarnuzzer³, Michael A. Horan², Gregory S. Schultz³ & Mark W.J. Ferguson¹



 
Expression of truncated utrophin leads to major functional improvements in dystrophin-deficient muscles of mice  p 1216
Nicolas Deconinck^1,*, Jonathon Tinsley^2,*, Fabienne De Backer¹, Rosie Fisher², David Kahn¹, Steve Phelps², Kay Davies² & Jean-Marie Gillis¹



 
Halting angiogenesis suppresses carcinoma cell invasion  p 1222
Mihaela Skobe¹, Patricia Rockwell², Neil Goldstein², Silvia Vosseler¹ & Norbert E. Fusenig¹



 
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction  p 1228
Gloria I. Perez¹, C. Michael Knudson², Lucy Leykin¹, Stanley J. Korsmeyer² & Jonathan L. Tilly¹



 
Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p53-independent induction of p21^WAF1/CIP1 via C/EBPbeta  p 1233
Rebecca Chinery^1,2, Jeffrey A. Brockman², Mark O. Peeler⁴, Yu Shyr^3,5, R. Daniel Beauchamp^1,4,5 & Robert J. Coffey^1,2,5



 
HIV-1 induction of CD40 on endothelial cells promotes the outgrowth of AIDS-associated B-cell lymphomas  p 1242
Ashlee V. Moses¹, Sally E. Williams¹, Joanne G. Strussenberg¹, Marika L. Heneveld², Rebecca A. Ruhl¹, Antony C. Bakke³, Grover C. Bagby² & Jay A. Nelson¹



 
HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals  p 1250
Sandra Mazzoli¹, Daria Trabattoni², Sergio Lo Caputo¹, Stefania Piconi³, Claudio Blé¹, Francesca Meacci¹, Stefania Ruzzante², Alessanda Salvi¹, Francesca Semplici¹, Renato Longhi⁴, Maria Luisa Fusi², Nadia Tofani¹, Mara Biasin², Maria Luisa Villa², Francesco Mazzotta¹ & Mario Clerici²



 
Increased sensitivity of HIV-1 antibody detection  p 1258
Howard B. Urnovitz, Jerrilyn C. Sturge & Toby D. Gottfried



 
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression  p 1259
Gabriella Scarlatti¹, Eleonora Tresoldi¹, Åsa Björndal³, Robert Fredriksson³, Claudia Colognesi¹, Hong Kui Deng⁴, Mauro S. Malnati², Anna Plebani⁵, Antonio G. Siccardi¹, Dan R. Littman⁴, Eva Maria Fenyö³ & Paolo Lusso²



 
A novel protein that participates in nonself discrimination of malignant cells by homologous complement  p 1266
Misako Matsumoto¹, Junji Takeda², Norimitsu Inoue², Tomoko Hara¹, Michiyo Hatanaka¹, Kazuhiko Takahashi³, Shigeharu Nagasawa³, Hitoshi Akedo¹ & Tsukasa Seya^1,4



 
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines  p 1271
Tracy M. Bryan¹, Anna Englezou¹, Luciano Dalla-Pozza², Melissa A. Dunham¹ & Roger R. Reddel¹



 
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein  p 1275
Jan Wijnholds¹, Raymond Evers¹, Manuel R. van Leusden¹, Carla A.A.M. Mol¹, Guido J.R. Zaman¹, Ulrich Mayer¹, Jos H. Beijnen², Martin van der Valk³, Paul Krimpenfort³ & Piet Borst¹



 
Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line  p 1280
David M. Bedwell^1,5, Anisa Kaenjak^1,5, Dale J. Benos^2,5, Zsuzsa Bebok^2,5, James K. Bubien^2,5, Jeong Hong^3,5, Albert Tousson^3,5, J.P. Clancy^2,4,5 & Eric J. Sorscher^2,4,5



 
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2  p 1285
Violetta Iotsova¹, Jorge Caamaño¹, James Loy², Yi Yang¹, Anne Lewin¹ & Rodrigo Bravo¹



 
book review

 
Sex on the Brain: THE BIOLOGICAL DIFFERENCES BETWEEN MEN AND WOMEN   p 1291
by Deborah Blum Reviewed by S. Marc Breedlove



 
Immunology: THE MAKING OF MODERN SCIENCE   p 1291
by Richard B. Gallagher & Jean Gilder Reviewed by Charles Janeway



 
Sex, Race, and Science

EUGENICS IN THE DEEP SOUTH   p 1292
by Edward J. Larson Reviewed by Jon Beckwith



 
new technology

 
New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors  p 1295
Forrest K. Ferrari, Xiao Xiao, Doug McCarty & Richard J. Samulski


 
on the market

 
On The Market  p 1297