Table of Contents

August 1996 Volume 2 Number 8 p 944     editorial   Vindication is sweet, but not sufficient  p 831   letters to the editor   Plasma HIV viremia and viral load in lymph nodes  p 832   A closer look at malaria in India  p 833   Vitamin D receptors and hyperparathyroidism  p 834   The greatest threat of all  p 834   news   Japan's change of heart  p 835   France's CNRS goes au naturelle  p 836   Cancer survivors get new office  p 836   Banking on safe blood  p 837   A tough ruling for medical device manufacturers  p 837   Indian experts clash over toothpaste flouridation  p 838   HHMI supports post-Soviet bloc researchers  p 838   MRC makes move to reap what it sows  p 839   Getting a fix on Australian health care  p 840   Kan pushes the pill in Japan  p 842   commentary   The Baltimore affair: Let's not forget what went wrong  p 843 Donald Kennedy   Work on your theories!  p 844 Lars Holmberg & Michael Baum   Thalassemia -- a global public health problem  p 847 D.J. Weatherall & J.B. Clegg   news & views   New clues to Alzheimer's disease: Unraveling the roles of amyloid and tau  p 850 Bruce A. Yankner   Seeing how we hear  p 852 Atsushi Momose1 & Tohoru Takeda2   An ace up the sleeve of the cholera bacterium  p 853 Stephen H. Richardson & Daniel J. Wozniak   Chlamydia in coronary plaques -- hidden culprit or harmless hobo?  p 856 Lo�c Capron   Genetic vaccination: The advantages of going naked  p 857 Vipin Kumar & Eli Sercarz   Ventricular remodeling: Hype or hope?  p 859 Patrick M. McCarthy   Will there be noise in their ears?  p 860 Frank Moss1, Faye Chiou-Tan3 & Rainer Klinke2   Seeking the cause of Kaposi's sarcoma  p 862 J.J. O'Leary   article   Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease  p 864 D. Scheuner1, C. Eckman1,2, M. Jensen3, X. Song4, M. Citron5, N. Suzuki6, T.D. Bird7,12, J. Hardy14, M. Hutton14, W. Kukull8, E. Larson9, E. Levy-Lahad9,13, M. Viitanen3, E. Peskind10,13, P. Poorkaj7,13, G. Schellenberg7,9,11,13, R. Tanzi15, W. Wasco15, L. Lannfelt3, D. Selkoe5 & S. Younkin2   Glycosylation of microtubule-associated protein tau: An abnormal posttranslational modification in Alzheimer's disease  p 871 Jian-Zhi Wang, Inge Grundke-Iqbal & Khalid Iqbal   Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells  p 876 Helmut Hanenberg1, Xiang Li Xiao1, Dagmar Dilloo2, Kimikazu Hashino3, Ikunoshin Kato3 & David A. Williams1,4   Microencapsulated genetically engineered live E. coli DH5 cells administered orally to maintain normal plasma urea level in uremic rats  p 883 S. Prakash & T.M.S. Chang   Vaccination against tuberculosis by DNA injection  p 888 Ricardo E. Tascon, M. Jo Colston, Silvia Ragno, Evangelos Stavropoulos, Derek Gregory & Douglas B. Lowrie   Immunogenicity and protective efficacy of a tuberculosis DNA vaccine  p 893 Kris Huygen1, Jean Content1, Olivier Denis1, Donna L. Montgomery2, Anne M. Yawman2, R. Randall Deck2, Corrille M. DeWitt2, Ian M. Orme3, Susan Baldwin3, Celine D'Souza3, Annie Drowart4, Evelyne Lozes1, Paul Vandenbussche1, Jean-Paul Van Vooren4, Margaret A. Liu2 & Jeffrey B. Ulmer2   Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity  p 899 Ari Waisman1, Pedro J. Ruiz1, David L. Hirschberg2,3, Avraham Gelman1, Jorge R. Oksenberg4, Stefan Brocke3, Felix Mor1, Irun R. Cohen1 & Lawrence Steinman1,3   Large clonal expansions of CD8+ T cells in acute infectious mononucleosis  p 906 Margaret F.C. Callan1, Neil Steven2, Pete Krausa1, Jamie D.K. Wilson1, Paul A.H. Moss1, Geraldine M. Gillespie1, John I. Bell1, Alan B. Rickinson2 & Andrew J. McMichael1   Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer   p 912 Iakovos Sigalas1, A. Hilary Calvert1, John J. Anderson2, David E. Neal3 & John Lunec1   The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission  p 918 Dean H. Kedes1, Eva Operskalski2, Michael Busch3, Robert Kohn4, Jennifer Flood4 & Don Ganem1   KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma  p 925 Shou-Jiang Gao1, Lawrence Kingsley2, Ming Li3, Wei Zheng3, Carlo Parravicini4, John Ziegler5, Robert Newton6, Charles R. Rinaldo2, Alfred Saah7, John Phair8, Roger Detels9, Yuan Chang3 & Patrick S. Moore1   Enhancement of vowel coding for cochlear implants by addition of noise  p 928 Robert P. Morse & Edward F. Evans   Applying very high resolution microfocus X-ray CT and 3-D reconstruction to the human auditory apparatus  p 933 Takashi Shibata & Teiko Nagano   book review   Dictators in the Mirror of Medicine: Napoleon, Hitler and Stalin  p 936 by Anton Neumayr translated by David J. Parent Medi-Ed Press Bloomington, Illinois, $34.95 ISBN: 0-7167-6014-2, 1995   Waking Up, Fighting Back: The Politics of Breast Cancer  p 937 by Roberta Altman Little, Brown and Company Boston, Massachusetts, $24.95 ISBN: 0-316-03532-7, 1996   new technology   Biomedical three-dimensional holographic microimaging at visible, ultraviolet and X-ray wavelengths  p 939   Semiconductor microlasers: A new approach to cell-structure analysis942  p 942   On the Market  p 944