To commemorate our tenth year, Nature Medicine will feature a series of articles highlighting major biomedical achievements of the past decade. We have commissioned Historical Perspectives on key topics that have seen significant progress since the inception of the journal. These include therapeutic approaches, neuroscience, metabolic diseases, cancer, infectious diseases, cardiovascular diseases and immunology. Experts in each discipline will write the articles, and the series will be published over the course of 2004.

To further celebrate these fields, Historical News and Views on groundbreaking papers from the last ten years will accompany these perspectives. Each issue will also contain topically-related news stories and profiles featuring outstanding scientists in each field. The collected content of the year will be available on a continually updated website. This Web Focus will also give free access to classic papers from Nature Medicine that have helped define the field. We hope you will enjoy these special issues. Please join us in celebrating ten outstanding years at Nature Medicine.