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Nature Medicine 9, 1118 - 1119 (2003)
doi:10.1038/nm0903-1118
Escherichia coli gets the message
Klaus Winzer1 & Paul Williams1
- Klaus Winzer and Paul Williams are at the Institute of Infection, Immunity, and Inflammation, Queen's Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK. Paul Williams is also at the School of Pharmaceutical Sciences, University Park, University of Nottingham, Nottingham NG7 2RD, UK e-mail: klaus.winzer@nottingham.ac.uk or e-mail: paul.williams@nottingham.ac.uk
Abstract
Bacterial signaling systems have come into vogue lately as mediators of successful interactions with the host. Now it appears that human hormones present in the gut interact with one such signaling system.
The growing repertoire of cell-to-cell communication systems in bacteria continues to bring new surprises. In their latest study, Sperandio et al.1 provide evidence for a link between a cell-cell signaling system in enterohemorrhagic Escherichia coli and the host hormone epinephrine (adrenaline).
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