Stephen Safe is in the Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, Texas 77843, USA. ssafe@cvm.tamu.edu
Cadmium is a toxic environmental pollutant that has worrisome estrogenic effects in cell culture. New data from rats show that cadmium can act as an estrogen mimic in the whole animal, inducing conditions ranging from uterine hyperplasia to early onset of puberty (pages 1081−1084).