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News and Views
Nature Medicine  9, 512 - 513 (2003)
doi:10.1038/nm0503-512

Mastering innate immunity

Robert M. Strieter

Departments of Medicine and Pathology and Laboratory Medicine, Division of Pulmonary and Critical Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA rstrieter@mednet.ucla.edu

Cells of the innate immune system get energy almost entirely from glycolysis, enabling survival under a variety of harsh conditions. The transcriptional regulator HIF-1 is now placed at the center of metabolic control in these cells.

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Immunology: Oxygen and the inflammatory cell
Nature News and Views (17 Apr 2003)

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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