Nature Medicine9, 389 - 390 (2003)
Published online: 17 March 2003; | doi:10.1038/nm847
Alzheimer disease's double-edged vaccine
S. M. Greenberg, B. J. Bacskai
& B. T. Hyman
Figure 1.Model of response to A vaccine. Areas of cerebral cortex in a treated AD patient suggest clearance of neuritic plaques and inflammation surrounding some amyloid-containing vessel segments. The data suggested that there was no effect on non-A lesions such as neurofibrillary tangles and dystrophic neurites. The foci of microglia in these regions may represent cells involved in the phagocytotic removal of A.
vaccine.
lesions such as neurofibrillary tangles and dystrophic neurites. The foci of microglia in these regions may represent cells involved in the phagocytotic removal of A