 | Figure 3
Nature Medicine
9, 213 - 219 (2003)
Published online: 13 January 2003; | doi:10.1038/nm820
Reciprocal regulation of inflammation and lipid metabolism by liver X receptorsSean B. Joseph, Antonio Castrillo, Bryan A. Laffitte, David J. Mangelsdorf
& Peter Tontonoz | | | | Figure 3. Transcriptional profiling of LXR agonist effects in LPS-activated macrophages.
Graphic representation of gene expression changes in macrophages treated with 100 ng/ml LPS and vehicle or synthetic LXR agonist GW3965 (2  M) as indicated. Genes involved in inflammation or lipid metabolism were selected based on ligand-dependent changes in expression in wild-type, Nr1h3-/- and Nr1h2-/-, but not Nr1h3-/-Nr1h2-/-, cells.
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