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Nature Medicine 9, 1455 - 1456 (2003)
doi:10.1038/nm1203-1455
Dilated cardiomyopathy: learning to live with yourself
W Robb MacLellan1 & Aldons J Lusis1
- W. Robb MacLellan and Aldons J. Lusis are in the Department of Medicine, Division of Cardiology, Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095-1679, USA. e-mail: rmaclellan@mednet.ucla.edu or e-mail: jlusis@mednet.ucla.edu
Abstract
Two new studies outline the causes of dilated cardiomyopathy, an autoimmune reaction that slowly destroys the heart (pages 1477–1483 and 1484–1490).
The most common reason for heart transplantation in young adults and children is dilated cardiomyopathy, a poorly understood disorder in which the ventricular chambers of the heart enlarge. Dilated cardiomyopathy is thought to arise, in the vast majority of cases, through an initial infection by adenovirus or specific strains of coxsackie virus.
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