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Nature Medicine  9, 1457 - 1458 (2003)
doi:10.1038/nm1203-1457

Anti-steroid takes aim at neuropathy

Peter De Jonghe & Vincent Timmerman

Peter De Jonghe and Vincent Timmerman are in the Molecular Genetics Department, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Antwerpen, B-2610, Belgium. peter.dejonghe@ua.ac.be

The most common form of inherited peripheral neuropathy results from overexpression of a single gene. Simple application of an antiprogesterone drug can reduce gene expression and alleviate symptoms in a rat model (pages 1533−1537).

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RESEARCH
Therapeutic administration of progesterone antagonist in a model of Charcot-Marie-Tooth disease (CMT-1A)
Nature Medicine Letters (01 Dec 2003)

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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