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Nature Medicine 9, 1354 - 1356 (2003)
doi:10.1038/nm1103-1354
Cancer vaccine targets leukemia
John Donnelly1
- John Donnelly is at Chiron Vaccines, 4560 Horton Street, Emeryville, California 94608, USA. e-mail: John_Donnelly@chiron.com
Abstract
Effective cancer vaccines targeted against specific antigens have eluded researchers for decades. When combined with a drug, one such vaccine now shrinks tumors in a mouse model of promyelocytic leukemia (pages 1413–1417).
Scientists have sought to use immunization as a method of treating cancer since the beginning of immunobiology. Over many decades, various approaches to eliciting both innate and acquired immune responses against tumors have been tried, some with a degree of success.
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