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Nature Medicine 9, 1350 - 1351 (2003)
doi:10.1038/nm1103-1350

Macrophages eyed in macular degeneration

J V Forrester1

  1. J.V. Forrester is in the Department of Ophthalmology, University of Aberdeen Medical School, Foresterhill, Aberdeen, AB25 2ZD, UK. e-mail: j.forrester@abdn.ac.uk


A new animal model for macular degeneration begins to reveal the inner workings of the delicate system of inflammatory checks and balances underlying this form of vision loss (pages 1390–1397).


The eye is an exquisitely engineered organ but, like any delicate instrument, it wears as it ages. Damage to the macula, an area rich in cone photoreceptors, leads to age-related macular degeneration (AMD) and the blurring of the world for millions of people1.

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REFERENCE
Macular Degeneration, Age Related
Nature Encyclopaedia of Life Sciences

REVIEWS
Ophthalmic drug discovery
Nature Reviews Drug Discovery Review (01 Jun 2003)

RESEARCH
An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice
Nature Medicine Article (01 Nov 2003)
Towards an understanding of age-related macular disease
Eye Original Article (01 May 2003)
A non-idiopathic case of polypoidal choroidal vasculopathy
Eye Letter to Editor (01 Jan 2004)
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