John D. McKinney and James E. Gomez are in the Laboratory of Infection Biology, The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA. mckinney@rockefeller.edu or gomezj@rockefeller.edu
M. tuberculosis persists in the body, sequestered inside macrophages and subverting the phagocytic machinery to create a membrane-bound home. Microarray profiling studies reveal how the bacterium settles into its new environment.