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Nature Medicine  8, 934 - 936 (2002)
doi:10.1038/nm0902-934

Keeping telomerase in its place

Richard S. Maser & Ronald A. DePinho

Department of Adult Oncology, Dana-Farber Cancer Institute, and Departments of Medicine and Genetics, Harvard Medical School Boston, Massachusetts, USA ron_depinho@dfci.harvard.edu

A new study shows that TERT, a component of telomerase, shuttles between nuclear compartments during the cell cycle. TERT localization is disrupted in cancer and following ionizing radiation, perhaps affecting genome stability.

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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