Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), CNRS/INSERM/ULP, Parc d'Innovation, Illkirch, France auwerx@igbmc.u-strasbg.fr
Before leaving the body, cholesterol is converted to bile acids. Two studies implicate the nuclear receptor SHP as a major player in bile-acid production—but not the only one.
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is an essential regulator of bile acid and plasma cholesterol metabolism
