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Nature Medicine 8, 560 - 561 (2002)
doi:10.1038/nm0602-560

The healing touch of epidermal T cells

Willi K. Born1 & Rebecca L. O'Brien1

  1. Department of Immunology National Jewish Medical and Research Center Denver, Colorado, USA e-mail: bornw@njc.org


After skin wounding, tissue repair requires the division and growth of skin epithelial cells. A new study in mice shows that specialized T lymphocytes found in skin, epidermal gammadelta T cells, are induced by wounding to secrete growth factors that accelerate wound healing.


Over the last decades, it has become clear that the immune system has an important role in wound repair. Defining exactly how immune cells and their factors influence tissue regeneration is a focus of current investigation.

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