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Nature Medicine  8, 480 - 484 (2002)
doi:10.1038/nm0502-480

A pivotal role of cytosolic phospholipase A2 in bleomycin-induced pulmonary fibrosis

Takahide Nagase, Naonori Uozumi, Satoshi Ishii, Yoshihiro Kita, Hiroshi Yamamoto, Eijiro Ohga, Yasuyoshi Ouchi & Takao Shimizu
 
Figure 1 thumbnailFigure 1.
Physiological roles of cPLA2 in IPF induced by bleomycin treatment.

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Photomicrograph of lung tissues from wild-type and cPLA2-null mice 14 d after bleomycin administration.

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Figure 3 thumbnailFigure 3.
Histopathological roles of cPLA2 in pulmonary fibrosis induced by bleomycin treatment.

Full FigureFull Figure and legend (7K)		 Figure 4 thumbnailFigure 4.
Roles of cPLA2 in leukocyte infiltration associated with pulmonary fibrosis induced by bleomycin treatment.

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Table 1 thumbnailTable 1.
Physiological and biochemical data after saline or bleomycin treatment.

Full TableFull Table		 Table 2 thumbnailTable 2.
Roles of PAF in bleomycin-induced pulmonary fibrosis.

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