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News and Views
Nature Medicine  8, 213 - 214 (2002)
doi:10.1038/nm0302-213

Are somatic stem cells pluripotent or lineage-restricted?

Kevin A. D'Amour & Fred H. Gage

Laboratory of Genetics, Salk Institute La Jolla, California, USA
gage@salk.edu

The finding that fetal mouse neural stem cells do not differentiate into hematopoietic cells contradicts findings from earlier reports and adds to the controversy regarding the rigor of the experimental methods used to demonstrate the differentiation repertoire of stem cells. (pages 268−273)

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Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations
Nature Medicine Article (01 Mar 2002)

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