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Nature Medicine  8, 179 - 183 (2002)
doi:10.1038/nm0202-179

Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity

Ellen L. Air, Mathias Z. Strowski, Stephen C. Benoit, Stacey L. Conarello, Gino M. Salituro, Xiao-Ming Guan, Kun Liu, Stephen C. Woods & Bei B. Zhang
 
Figure 1 thumbnailFigure 1.
Centrally administered Cpd 1 reduces food intake and body weight.

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 Figure 2 thumbnailFigure 2.
Cpd 2 attenuates body weight gain and adiposity in ICR mice fed the HFD.

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Table 1 thumbnailTable 1.
Cpd 2 reduces indices of obesity and improves insulin sensitivity

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