Institute of Medical Chemistry and Biochemistry University of Innsbruck, Austria
wolfgang.doppler@uibk.ac.at
The isoform of the IB protein kinase has been identified as the missing link in a signaling pathway that controls mammary epithelial proliferation via the cell-cycle regulator cyclin D1. This new player may provide a promising target for inhibiting cyclin D1 expression, which is elevated in 50% of breast malignancies.
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isoform of the I
B protein kinase has been identified as the missing link in a signaling pathway that controls mammary epithelial proliferation via the cell-cycle regulator cyclin D1. This new player may provide a promising target for inhibiting cyclin D1 expression, which is elevated in 50% of breast malignancies.
B IN CANCER: FROM INNOCENT BYSTANDER TO MAJOR CULPRIT
