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| A comprehensive and authoritative overview of the field focused on areas undergoing particularly rapid progress. |
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| Editorial | Top |
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Early warning p1183 doi:10.1038/nm1102-1183 Full text | PDF
(37K)
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| Letters to Editor | Top |
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Pharmacological prevention of Parkinson disease in Drosophila pp1185 - 1186 Pavan K. Auluck
& Nancy M. Bonini doi:10.1038/nm1102-1185 Full text | PDF
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Hypothalamic gray matter changes in narcoleptic patients pp1186 - 1188 B. Draganski, P. Geisler, G. Hajak, G. Schuierer, U. Bogdahn, J. Winkler
& A. May doi:10.1038/nm1102-1186 Full text | PDF
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| News | Top |
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Leukemia case triggers tighter gene-therapy controls p1189 Laura Bonetta doi:10.1038/nm1102-1189 Full text | PDF
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Big bucks for autism research p1190 Alan Dove doi:10.1038/nm1102-1190a Full text | PDF
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McClellan nominated to head FDA p1190 Alan Dove doi:10.1038/nm1102-1190b Full text | PDF
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More rare disease money pp1190 - 1191 Laura Bonetta doi:10.1038/1102-1190c Full text | PDF
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Genome scientists' paths diverge p1191 Karen Birmingham
& Marlene Cimons doi:10.1038/nm1102-1191a Full text | PDF
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MIM HQ moves continent p1191 Alan Dove doi:10.1038/nm1102-1191b Full text | PDF
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Nadia Rosenthal p1192 Karen Birmingham doi:10.1038/nm1102-1192 Abstract | Full text | PDF
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| Book Reviews | Top |
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What It Means to Be 98% Chimpanzee: Apes, People, and Their Genes p1193 Reviewed by: Reviewed by Randolph M. Nesse doi:10.1038/nm1102-1193 Full text | PDF
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The Creation of Psychopharmacology p1194 Reviewed by: Reviewed by Philip Seeman doi:10.1038/nm1102-1194 Full text | PDF
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| News and Views | Top |
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New hope for Alzheimer disease vaccine pp1195 - 1196 Christian Haass doi:10.1038/nm1102-1195 Abstract | Full text | PDF
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See also: Article by McLaurin et al. | Article by Hock et al. |
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Converting p53 from a killer into a healer pp1196 - 1198 Andrei V. Gudkov doi:10.1038/nm1102-1196 Abstract | Full text | PDF
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Parasite packs a punch pp1198 - 1199 Peter R. Preiser doi:10.1038/nm1102-1198 Abstract | Full text | PDF
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See also: Article by Mota et al. |
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Muscling in on rhabdomyosarcoma pp1200 - 1201 Webster K. Cavenee doi:10.1038/nm1102-1200 Abstract | Full text | PDF
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See also: Article by Sharp et al. |
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Two-sided T cell p1201 Charlotte Schubert doi:10.1038/nm1102-1201 Full text | PDF
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Bad chaperone pp1202 - 1203 Sally A. Lewis
& Nicholas J. Cowan doi:10.1038/nm1102-1202 Abstract | Full text | PDF
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Circadian rhythm beats back cancer p1203 Charlotte Schubert doi:10.1038/nm1102-1203 Full text | PDF
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A new regulatory pathway for fragile X syndrome? pp1204 - 1205 R. Scott Hansen
& Charles D. Laird doi:10.1038/nm1102-1204 Abstract | Full text | PDF
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Research news p1206 Charlotte Schubert doi:10.1038/nm1102-1206 Full text | PDF
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| Sponsor's Foreword | Top |
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Focus on Atherosclerosis From the sponsors p1208 Eleanor A. O'Rangers doi:10.1038/nm1102-1208 Abstract | Full text | PDF
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| Foreword | Top |
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Focus on Atherosclerosis At the heart of atherosclerosis p1209 Ushma Savla doi:10.1038/nm1102-1209 Full text | PDF
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| Perspective | Top |
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Focus on Atherosclerosis Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime pp1211 - 1217 Daniel Steinberg doi:10.1038/nm1102-1211 Abstract | Full text | PDF
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| Reviews | Top |
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Focus on Atherosclerosis Innate and acquired immunity in atherogenesis pp1218 - 1226 Christoph J. Binder, Mi-Kyung Chang, Peter X. Shaw, Yury I. Miller, Karsten Hartvigsen, Asheesh Dewan
& Joseph L. Witztum doi:10.1038/nm1102-1218 Abstract | Full text | PDF
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Focus on Atherosclerosis Platelets in atherothrombosis pp1227 - 1234 Zaverio M. Ruggeri doi:10.1038/nm1102-1227 Abstract | Full text | PDF
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Focus on Atherosclerosis The macrophage foam cell as a target for therapeutic intervention pp1235 - 1242 Andrew C. Li
& Christopher K. Glass doi:10.1038/nm1102-1235 Abstract | Full text | PDF
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Focus on Atherosclerosis The liver X receptor gene team: Potential new players in atherosclerosis pp1243 - 1248 Joyce J. Repa
& David J. Mangelsdorf doi:10.1038/nm1102-1243 Abstract | Full text | PDF
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Focus on Atherosclerosis Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies pp1249 - 1256 Victor J. Dzau, Ruediger C. Braun-Dullaeus
& Daniel G. Sedding doi:10.1038/nm1102-1249 Abstract | Full text | PDF
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Focus on Atherosclerosis Stabilization of atherosclerotic plaques: New mechanisms and clinical targets pp1257 - 1262 Peter Libby
& Masanori Aikawa doi:10.1038/nm1102-1257 Abstract | Full text | PDF
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| Articles | Top |
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Therapeutically effective antibodies against amyloid- peptide target amyloid- residues 4−10 and inhibit cytotoxicity and fibrillogenesis pp1263 - 1269 J. McLaurin, R. Cecal, M.E. Kierstead, X. Tian, A.L. Phinney, M. Manea, J.E. French, M.H.L. Lambermon, A.A. Darabie, M.E. Brown, C. Janus, M.A. Chishti, P. Horne, D. Westaway, P.E. Fraser, H.T.J. Mount, M. Przybylski
& P. St George-Hyslop Published online: 15 October 2002 | doi:10.1038/nm790 Abstract | Full text | PDF
(625K)
See also: News and Views by Haass |
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Generation of antibodies specific for -amyloid by vaccination of patients with Alzheimer disease pp1270 - 1275 Christoph Hock, Uwe Konietzko, Andreas Papassotiropoulos, Axel Wollmer, Johannes Streffer, Ruth C. von Rotz, Gabriela Davey, Eva Moritz
& Roger M. Nitsch Published online: 15 October 2002 | doi:10.1038/nm783 Abstract | Full text | PDF
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See also: News and Views by Haass |
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Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis pp1276 - 1280 Richard Sharp, Juan A. Recio, Chamelli Jhappan, Toshiyuki Otsuka, Shiquan Liu, Yanlin Yu, Wenjing Liu, Miriam Anver, Fariba Navid, Lee J. Helman, Ronald A. DePinho
& Glenn Merlino Published online: 7 October 2002 | doi:10.1038/nm787 Abstract | Full text | PDF
(697K)
See also: News and Views by Cavenee |
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Functional PPAR- receptor is a novel therapeutic target for ACTH-secreting pituitary adenomas pp1281 - 1287 Anthony P. Heaney, Manory Fernando, William H. Yong
& Shlomo Melmed Published online: 15 October 2002 | doi:10.1038/nm784 Abstract | Full text | PDF
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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase pp1288 - 1295 T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, S. Yamashita, M. Noda, S. Kita, K. Ueki, K. Eto, Y. Akanuma, P. Froguel, F. Foufelle, P. Ferre, D. Carling, S. Kimura, R. Nagai, B.B. Kahn
& T. Kadowaki Published online: 07 October 2002 | doi:10.1038/nm788 Abstract | Full text | PDF
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| Supplementary Information |
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Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor pp1296 - 1302 Mauro Perretti, Nan Chiang, Mylinh La, Iolanda M. Fierro, Stefano Marullo, Stephen J Getting, Egle Solito
& Charles N. Serhan Published online: 07 October 2002 | doi:10.1038/nm786 Abstract | Full text | PDF
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Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor pp1303 - 1309 Francisco J. Naya, Brian L. Black, Hai Wu, Rhonda Bassel-Duby, James A. Richardson, Joseph A. Hill
& Eric N. Olson Published online: 15 October 2002 | doi:10.1038/nm789 Abstract | Full text | PDF
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Activation and function of cyclin T−Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy pp1310 - 1317 Motoaki Sano, Maha Abdellatif, Hidemasa Oh, Min Xie, Luigi Bagella, Antonio Giordano, Lloyd H. Michael, Francesco J. DeMayo
& Michael D. Schneider Published online: 30 September 2002 | doi:10.1038/nm778 Abstract | Full text | PDF
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Migration through host cells activates Plasmodium sporozoites for infection pp1318 - 1322 Maria M. Mota, Julius C.R. Hafalla
& Ana Rodriguez Published online: 15 October 2002 | doi:10.1038/nm785 Abstract | Full text | PDF
(304K)
See also: News and Views by Preiser |
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| New Technology | Top |
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Automated subcellular localization and quantification of protein expression in tissue microarrays pp1323 - 1328 Robert L. Camp, Gina G. Chung
& David L. Rimm Published online: 21 October 2002 | doi:10.1038/nm791 Abstract | Full text | PDF
(671K)
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On the market p1328 doi:10.1038/nm1102-1328 Full text | PDF
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| Erratum | Top |
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Streptococcus pyogenes and phagocytic killing p1329 U. von Pawel-Rammingen, B.P. Johansson, H. Tapper
& L. Björck doi:10.1038/nm1102-1329a Full text | PDF
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| Corrigenda | Top |
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Loss of HIF-2 and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice p1329 V. Compernolle, K. Brusselmans, T. Acker, P. Hoet, M. Tjwa, H. Beck, S. Plaisance, Y. Dor, E. Keshet, F. Lupu, B. Nemery, M. Dewerchin, P. Van Veldhoven, K. Plate, L. Moons, D. Collen
& P. Carmeliet doi:10.1038/nm1102-1329b Full text | PDF
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Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring p1329 F. Paris, G.I. Perez, Z. Fuks, A. Haimovitz-Friedman, H. Nguyen, M. Bose, A. Ilagan, P.A. Hunt, W.F. Morgan, J.L. Tilly
& R. Kolesnick doi:10.1038/nm1102-1329c Full text | PDF
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