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Nature Medicine 8, 1195 - 1196 (2002)
doi:10.1038/nm1102-1195

New hope for Alzheimer disease vaccine

Christian Haass1

  1. Adolf-Butenandt Institute, Department of Biochemistry Laboratory for Alzheimer's and Parkinson's Disease Research Ludwig-Maximilians University Munich, Germany e-mail: chaass@pbm.med.uni-muenchen.de


Clinical trials of a vaccine against Alzheimer disease came to an abrupt halt this year when several patients developed inflammation in the brain. Now, the first data from the trial and a mouse study brighten the outlook for this spectacular and simple treatment approach (pages 1263–1269 and 1270–1275).


Major advances in modern medicine allow us to live much longer than our ancestors. Unfortunately, many are unable to enjoy the additional years due to the devastations of Alzheimer disease (AD), which culls neurons in brain regions required for our intellectual abilities.

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