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Nature Medicine  8, 1218 - 1226 (2002)
doi:10.1038/nm1102-1218

Innate and acquired immunity in atherogenesis

Christoph J. Binder, Mi-Kyung Chang, Peter X. Shaw, Yury I. Miller, Karsten Hartvigsen, Asheesh Dewan & Joseph L. Witztum

Department of Medicine, University of California San Diego, La Jolla, California, USA

Correspondence should be addressed to Joseph L. Witztum jwitztum@ucsd.edu
Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is now apparent that the immune system also plays an important role. Uncovering the mechanisms by which specific components of the immune system impact atherogenesis will not only provide new insights into the pathogenesis of lesion formation, but could also lead to novel therapeutic approaches that involve immune modulation.

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REFERENCE
Cardiovascular Disease and Congenital Heart Defects
Nature Encyclopaedia of Life Sciences

REVIEWS
Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime
Nature Medicine Perspective (01 Nov 2002)
 See all 4 matches for Reviews

NEWS AND VIEWS
eLiXiRs for restraining inflammation
Nature Medicine News and Views (01 Feb 2003)
Cholesterol esters and atherosclerosis-a game of ACAT and mouse
Nature Medicine News and Views (01 Dec 2000)
 See all 4 matches for News And Views

RESEARCH
Reply to "Humoral immunity and atherosclerosis"
Nature Medicine Letters to Editor (01 Mar 2003)
 See all 10 matches for Research

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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