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News and Views
Nature Medicine  8, 1082 - 1083 (2002)
doi:10.1038/nm1002-1082

Attacked from within, blood thins

Wadie F. Bahou

Departments of Medicine and Program in Genetics, State University of New York, Stony Brook, New York, USA wbahou@notes.cc.sunysb.edu

Thrombin leads to blood clotting through activation of specialized G protein−coupled receptors. In mice, small peptides call pepducins inhibit thrombin receptors and prevent blood clotting (pages 1161−1165).

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Cardiovascular biology: Platelets and proteases
Nature News and Views (06 Sep 2001)

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Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
Nature Medicine Article (01 Oct 2002)
Reply to "Inhibition of platelet thromboxane receptor function by a thrombin receptor–targeted pepducin"
Nature Medicine Correspondence (01 Dec 2003)
Inhibition of platelet thromboxane receptor function by a thrombin receptor–targeted pepducin
Nature Medicine Correspondence (01 Dec 2003)

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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