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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Medicine  8, 1080 - 1082 (2002) doi:10.1038/nm1002-1080 Inflammation intersection: gp130 balances gut irritation and stomach cancer Timothy C. Wang1 & James R. Goldenring2 1  Gastroenterology Division and Department of Medicine, University of Massachusetts Medical Center, Worcester, Massachusetts, USA timothy.wang@umassmed.edu 2  Vanderbilt-Ingram Cancer Center and Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee, USA The stomach and the intestine respond differently to inflammation. Work on the cytokine receptor gp130 helps explain why cancer develops in the stomach and inflammatory bowel disease hits the intestine (pages 1089−1097). MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REVIEWS Trefoil factors: initiators of mucosal healing Nature Reviews Molecular Cell Biology Review (01 Sep 2003)  See all 2 matches for Reviews RESEARCH Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice Nature Medicine Article (01 Oct 2002) Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells Oncogene Original Article (17 Jul 2003) Expression of Cytoplasmic TFF2 Is a Marker of Tumor Metastasis and Negative Prognostic Factor in Gastric Cancer Laboratory Investigation Article (01 Sep 2003) Aberrant Expression of Trefoil Factor Family 1 in Biliary Epithelium in Hepatolithiasis and Cholangiocarcinoma Laboratory Investigation Research Article (01 Oct 2003)  See all 7 matches for Research  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Optimizing Sub-cellular Localization Tags Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... More Challenges Powered by: nature jobs Senior Medical Writer Cactus Global Mumbai 400053 India Section Chief of Molecular Diagnostics and Medical Director of Molecular Diagnotics Laboratory M. D. Anderson Cancer Center Houston, Texas, USA More science jobs Post a job for free Figures & Tables See also: Article by Tebbutt et al. Export citation Search buyers guide:   ADVERTISEMENT

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