1
State University of New York Downstate Medical Center, Brooklyn, New York, USA
2
Memorial Sloan−Kettering Cancer Center and Howard Hughes Medical Institute, New York, New York, USA j-massague@ski.mskcc.org
The cell-cycle inhibitor p27 is phosphorylated by the Akt kinase in breast cancer, according to three new studies. This phosphorylation keeps p27 in the cytoplasm and correlates with cancer aggressiveness (pages 1136−1144, 1145−1152 and 1153−1160.)
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