Molecular Carcinogenesis Group International Agency for Research on Cancer Lyon, France
hainaut@iarc.fr
Tumor-specific, 'signature' mutations of p53 have been identified in several cancers. The molecular basis of these tissue-specific selections has been poorly understood. A recent report sheds light on this issue by identifying the molecular basis of one such signature mutation found in adrenal cortical carcinomas.
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NEWS AND VIEWS TOUCHINGbase Nature Genetics News and Views (Touching Base) (01 Feb 2002)