Journal home
Advance online publication
Current issue
Archive
Press releases
Supplements
Focuses
Guide to authors
Online submissionOnline submission
For referees
Free online issue
Contact the journal
Subscribe
Advertising
work@npg
Reprints and permissions
About this site
For librarians
 
NPG Resources
Nature
Nature Reviews
Nature Immunology
Nature Cell Biology
Nature Genetics
news@nature.com
Nature Conferences
Dissect Medicine
NPG Subject areas
Biotechnology
Cancer
Chemistry
Clinical Medicine
Dentistry
Development
Drug Discovery
Earth Sciences
Evolution & Ecology
Genetics
Immunology
Materials Science
Medical Research
Microbiology
Molecular Cell Biology
Neuroscience
Pharmacology
Physics
Browse all publications
News and Views
Nature Medicine  8, 20 - 21 (2002)
doi:10.1038/nm0102-20

Shedding growth factors in cardiac hypertrophy

James K. Liao

Cardiovascular Division, Department of Medicine Brigham & Women's Hospital and Harvard Medical School Cambridge, Massachusetts, USA
jliao@rics.bwh.harvard.edu

The finding that cleavage and shedding of the membrane-bound heparin-binding epidermal growth factor by metalloproteases contribute to the hypertrophic process offers new insights for the treatment of cardiac hypertrophy and progression to heart failure. (pages 35−40)

MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated

REVIEWS
Cell communication networks: epidermal growth factor receptor transactivation as the paradigm for interreceptor signal transmission
Oncogene Reviews (30 Mar 2001)
G-proteins in growth and apoptosis: lessons from the heart
Oncogene Reviews (30 Mar 2001)
 See all 3 matches for Reviews

RESEARCH
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
Nature Medicine Article (01 Jan 2002)
Defective valvulogenesis in HB-EGF and TACE-null mice is associated with aberrant BMP signaling
The EMBO Journal Article (01 Jun 2003)
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
The EMBO Journal Article (15 May 2003)
 See all 4 matches for Research

 Top
Abstract
Previous | Next
Table of contents
Full textFull text
Download PDFDownload PDF
Send to a friendSend to a friend
Save this linkSave this link

Open Innovation Challenges

naturejobs

Figures & Tables
See also: Article by Asakura et al.
Export citation
natureproducts

Search buyers guide:

 
ADVERTISEMENT
 
Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
Journal home | Advance online publication | Current issue | Archive | Press releases | Supplements | Focuses | For authors | Online submission | For referees | Free online issue | About the journal | Contact the journal | Subscribe | Advertising | work@npg | Reprints and permissions | About this site | For librarians
Nature Publishing Group, publisher of Nature, and other science journals and reference works©2002 Nature Publishing Group | Privacy policy