Department of Pathology School of Medicine University of Washington Seattle, Washington, USA
nfausto@u.washington.edu
Patients with hepatitis C constitute the highest proportion of candidates for liver transplantation. The lack of small animal models for the disease has been a major stumbling block in understanding how hepatitis C and liver damage develop and in testing possible treatments. The report of infection of a mouse model with the hepatitis C virus is a significant and welcome achievement. (pages 927−933)