Cystic fibrosis salt/fluid controversy: In the thick of it
William B. Guggino
Professor of Physiology and Pediatrics Johns Hopkins University School of Medicine
Baltimore, Maryland, USA
wguggino@jhmi.edu
A new study shows that a mouse model of cystic fibrosis has lower levels of liquid on the surface of its airway epithelium which suggests that thickened airway secretions might have a role in the disease process and that rehydrating the airways might be of benefit to patients.
