Departments of Medicine and Dermatology, Johns Hopkins University School of Medicine 720 Rutland Avenue, Ross 1059 Baltimore, MD 21205
arosen@jhmi.edu
Mice with mutations in the Mer tyrosine kinase have deficits in the clearance of apoptotic thymocytes and increased titers of anti-DNA autoantibodies. These findings provide new in vivo evidence to suggest that impairments in clearance of apoptotic cells may underlie systemic autoimmunity.
