Access
To read this story in full you will need to login or make a payment (see right).
Nature Medicine 7, 493 - 496 (2001)
doi:10.1038/86573
Imaging mass spectrometry: A new technology for the analysis of protein expression in mammalian tissues
Markus Stoeckli1, Pierre Chaurand1, Dennis E. Hallahan1 & Richard M. Caprioli1
- Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Correspondence to: Richard M. Caprioli1 e-mail: r.caprioli@vanderbilt.edu
The molecular specificity and sensitivity of mass spectrometry (MS) has been employed in a new technology for direct mapping and imaging of biomolecules present in tissue sections. This technology has been developed using matrix-assisted laser desorption/ionization MS (MALDI MS)1 and has been initially targeted for the analysis of peptides and proteins present on or near the surface of tissue sections2.
To read this story in full you will need to login or make a payment (see right).
