Department of Clinical Genetics and Human Genetics Vrije Universiteit Medical Center Amsterdam, The Netherlands
h.joenje.humgen@med.vu.nl
The genetic basis of Fanconi anemia (FA) is mysterious and complex, as none of the five genes previously associated with the disorder have homology to genes encoding proteins of known function. The product of a sixth, newly-cloned FA-associated gene has been linked to BRCA1, and may finally offer some insight into the mechanism by which FA increases cancer susceptibility.
