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| Editorial |  Top |
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Will the US clone alone? p257
doi:10.1038/85352
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| Letters to Editor | Top |
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Perinatal omega-3 fatty acid deficiency affects blood pressure later in life pp258 - 259
Harrison S. Weisinger, James A. Armitage, Andrew J. Sinclair, Algis J. Vingrys, Peta L. Burns
& Richard S. Weisinger
doi:10.1038/85354
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(287K)
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Countering the 'counterattack' hypothesis p259
Nicholas P. Restifo
doi:10.1038/85357
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(26K)
See also: Commentary by O'Connell et al. |
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| News | Top |
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Scientists race to develop a blood test for vCJD p261
Laura Bonetta
doi:10.1038/85359
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(164K)
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More sensitive tests for BSE needed p261
Laura Bonetta
doi:10.1038/85361
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(164K)
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Experts predict bleak post-genomic era for drug R&D p262
Karen Birmingham
doi:10.1038/85364
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(410K)
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Experiments are destined for space p262
Laura Bonetta
doi:10.1038/85366
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(410K)
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Bush is a threat to US stem-cell research p263
Marlene Cimons
doi:10.1038/85369
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(221K)
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Election year boost for Australian R&D p263
Rada Rouse
doi:10.1038/85372
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(221K)
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US awaits FDA appointment p264
Alicia Ault
doi:10.1038/85374
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(280K)
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HHS advises IRBs on conflict issues p264
Tinker Ready
doi:10.1038/85377
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(280K)
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FDA to regulate tissue banks pp264 - 265
Tom Hollon
doi:10.1038/85379
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(286K)
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New reporting rules for gene therapy and xeno trials p265
Alan Dove
doi:10.1038/85382
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(22K)
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Limited gene therapy trials to restart p265
Tinker Ready
doi:10.1038/85384
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(22K)
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Sir John Sulston p266
Karen Birmingham
doi:10.1038/85386
Abstract | Full text | PDF
(312K)
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| Commentaries | Top |
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The early days of DNA sequences pp267 - 268
Fred Sanger
doi:10.1038/85389
Abstract | Full text | PDF
(150K)
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Legal Issues in Genomic Medicine pp268 - 271
Philip R. Reilly
doi:10.1038/85392
Abstract | Full text | PDF
(209K)
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Immune privilege or inflammation? Insights into the Fas ligand enigma pp271 - 274
Joe O'Connell, Aileen Houston, Michael W. Bennett, Gerald C. O'Sullivan
& Fergus Shanahan
doi:10.1038/85395
Abstract | Full text | PDF
(572K)
See also: Letters to Editor by Restifo |
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| Book Reviews | Top |
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Cracking the Genome p275
Reviewed by: Peter P. Tolias
doi:10.1038/85399
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(108K)
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Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine pp275 - 276
Reviewed by: Kenneth C. Anderson
doi:10.1038/85402
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(246K)
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| News and Views | Top |
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Putting the genes for type II diabetes on the map pp277 - 279
Katrine Almind, Alessandro Doria
& C. Ronald Kahn
doi:10.1038/85405
Abstract | Full text | PDF
(102K)
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Zeroing in on tolerance pp279 - 281
Anne M. Bowcock
& Michael Lovett
doi:10.1038/85408
Abstract | Full text | PDF
(56K)
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Pharmacogenetic applications of the Human Genome project pp281 - 283
Stephen B. Liggett
doi:10.1038/85411
Abstract | Full text | PDF
(74K)
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Gazing into a crystal ball−cancer therapy in the post-genomic era pp283 - 285
Mark J. Ratain
& Mary V. Relling
doi:10.1038/85414
Abstract | Full text | PDF
(389K)
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CYP3A genetics in drug metabolism pp285 - 287
Michel Eichelbaum
& Oliver Burk
doi:10.1038/85417
Abstract | Full text | PDF
(1,058K)
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The heart of genomics pp287 - 288
Michel Komajda
& Philippe Charron
doi:10.1038/85420
Abstract | Full text | PDF
(749K)
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Blood simple prion diagnostics pp289 - 290
Adriano Aguzzi
doi:10.1038/85423
Abstract | Full text | PDF
(111K)
See also: Article by Miele et al. |
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A role for fibronectin in self-repair after ischemic injury pp290 - 292
Deane F. Mosher
doi:10.1038/85426
Abstract | Full text | PDF
(66K)
See also: Article by Sakai et al. |
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The neglected ion: HCO3- pp292 - 293
Paul M. Quinton
doi:10.1038/85429
Abstract | Full text | PDF
(54K)
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Eyeing a new route along an old pathway pp294 - 295
Stanislav I. Tomarev
doi:10.1038/85432
Abstract | Full text | PDF
(62K)
See also: Article by Wang et al. |
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Research News p296
Bernd Pulverer, Karen Birmingham, Simon Nobel, Charlotte Wang
& Kristine Novak
doi:10.1038/85435
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(164K)
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| Articles | Top |
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Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming pp297 - 303
Joseph Wolfers, Anne Lozier, Graça Raposo, Armelle Regnault, Clotilde Théry, Carole Masurier, Caroline Flament, Stéphanie Pouzieux, Florence Faure, Thomas Tursz, Eric Angevin, Sebastian Amigorena
& Laurence Zitvogel
doi:10.1038/85438
Abstract | Full text | PDF
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Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype pp304 - 309
Nan Wang, Shravan K. Chintala, M. Elizabeth Fini
& Joel S. Schuman
doi:10.1038/85446
Abstract | Full text | PDF
(3,819K)
See also: News and Views by Tomarev |
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In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice pp310 - 316
Antonella Consiglio, Angelo Quattrini, Sabata Martino, Jean Charles Bensadoun, Diego Dolcetta, Alessandra Trojani, Giuliana Benaglia, Sergio Marchesini, Vincenzo Cestari, Alberto Oliverio, Claudio Bordignon
& Luigi Naldini
doi:10.1038/85454
Abstract | Full text | PDF
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ORP150 protects against hypoxia/ischemia-induced neuronal death pp317 - 323
Michio Tamatani, Tomohiro Matsuyama, Atsushi Yamaguchi, Noriaki Mitsuda, Yoshitane Tsukamoto, Manabu Taniguchi, Yong Ho Che, Kentaro Ozawa, Osamu Hori, Hiroyuki Nishimura, Atsuko Yamashita, Masaru Okabe, Hideki Yanagi, David M. Stern, Satoshi Ogawa
& Masaya Tohyama
doi:10.1038/85463
Abstract | Full text | PDF
(2,109K)
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Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. pp324 - 330
Takao Sakai, Kamin J. Johnson, Michihiro Murozono, Keiko Sakai, Marc A. Magnuson, Tadeuz Wieloch, Tobias Cronberg, Atsushi Isshiki, Harold P. Erickson
& Reinhard Fässler
doi:10.1038/85471
Abstract | Full text | PDF
(2,531K)
See also: News and Views by Mosher |
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Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability pp331 - 337
Kang Chen, Ildiko Aradi, Niklas Thon, Mariam Eghbal-Ahmadi, Tallie Z. Baram
& Ivan Soltesz
doi:10.1038/85480
Abstract | Full text | PDF
(132K)
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Clusterin contributes to caspase-3−independent brain injury following neonatal hypoxia-ischemia pp338 - 343
Byung Hee Han, Ronald B. DeMattos, Laura L. Dugan, Jeong Sook Kim-Han, Robert P. Brendza, John D. Fryer, Malca Kierson, John Cirrito, Kevin Quick, Judith A. K. Harmony, Bruce J. Aronow
& David M. Holtzman
doi:10.1038/85487
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MHC-I−restricted presentation of HIV-1 virion antigens without viral replication pp344 - 349
Florence Buseyne, Sylvie Le Gall, Claire Boccaccio, Jean-Pierre Abastado, Jeffrey D. Lifson, Larry O. Arthur, Yves Rivière, Jean-Michel Heard
& Olivier Schwartz
doi:10.1038/85493
Abstract | Full text | PDF
(594K)
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Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: A molecular link to cancer metastasis pp350 - 355
Chitra Subramanian, Murray A. Cotter II
& Erle S. Robertson
doi:10.1038/85499
Abstract | Full text | PDF
(669K)
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Changing the dosing schedule minimizes the disruptive effects of interferon on clock function pp356 - 360
Shigehiro Ohdo, Satoru Koyanagi, Hinako Suyama, Shun Higuchi
& Hironori Aramaki
doi:10.1038/85507
Abstract | Full text | PDF
(146K)
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A novel erythroid-specific marker of transmissible spongiform encephalopathies pp361 - 364
Gino Miele, Jean Manson
& Michael Clinton
doi:10.1038/85515
Abstract | Full text | PDF
(916K)
See also: News and Views by Aguzzi |
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Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies pp365 - 368
Werner Hoch, John McConville, Sigrun Helms, John Newsom-Davis, Arthur Melms
& Angela Vincent
doi:10.1038/85520
Abstract | Full text | PDF
(860K)
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| New Technology | Top |
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Imaging of amyloid- deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy pp369 - 372
Brian J. Bacskai, Stephen T. Kajdasz, Richard H. Christie, Cordelia Carter, Dora Games, Peter Seubert, Dale Schenk
& Bradley T. Hyman
doi:10.1038/85525
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(2,873K)
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Cell identification and isolation on the basis of cytokine secretion: A novel tool for investigating immune responses pp373 - 376
Victor Turcanu
& Neil A. Williams
doi:10.1038/85533
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(284K)
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A novel non-invasive, in vivo technique for the quantification of leukocyte rolling and extravasation at sites of inflammation in human patients pp376 - 379
Juha Kirveskari, Minna H. Vesaluoma, Jukka A.O. Moilanen, Timo M.T. Tervo, Matthew W. Petroll, Eeva Linnolahti
& Risto Renkonen
doi:10.1038/85538
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(448K)
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On the market pp379 - 380
doi:10.1038/85543
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(1,020K)
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