Departments of Microbiology and Medicine Columbia University, College of Physicians and Surgeons New York, New York, USA
JL45@columbia.edu
In a healthy cell, the normal business of Tsg101 protein is as part of the machinery for protein trafficking. It now emerges that two deadly but unrelated viruses, HIV-1 and Ebola, both subvert Tsg101 as an essential step in their life cycles—exiting a cell to restart the cycle of infection. (pages 1313−1319)
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