Molecular Cardiology Laboratory, Cardiology Division Department of Medicine and Department of Cell Biology Weill Medical College of Cornell University New York, New York, USA
ctbasson@med.cornell.edu
Holt−Oram syndrome has been associated with mutations in the T-box transcription factor TBX5, but little is known about the function of this protein or how mutations in it cause disease. A new mouse model of this syndrome will help to answer some of these questions.
