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Nature Medicine  7, 1182 - 1184 (2001)
doi:10.1038/nm1101-1182

How neutrophils recognize bacteria and move toward infection

Staffan Normark, Birgitta Henriques Normark & Mathias Hornef

Microbiology and Tumorbiology Center Karolinska Institutet Stockholm, Sweden
staffan.normark@smi.ki.se

The finding that CD38 mediates a sustained calcium signal inside neutrophils, which directs their movement toward lung tissue infected with pneumococcus bacteria suggests a new mechanism by which the immune system prevents the spread of bacterial infection. (pages 1209−1216)

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RESEARCH
Reply to 'Does neutrophil CD38 have a role in Ca++ signaling triggered by beta2 integrin?'
Nature Medicine Letters to Editor (01 Apr 2002)
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo
Nature Medicine Article (01 Nov 2001)
Does neutrophil CD38 have a role in Ca++ signaling triggered by beta2 integrin?
Nature Medicine Letters to Editor (01 Apr 2002)

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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