Department of Biochemistry The Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences, Technion−Israel Institute of Technology Haifa, Israel
c_tzachy@netvision.net.il
One neuronal characteristic of Parkinson disease is the presence of Lewy bodies−intracytoplasmic accumulations of protein. A new study draws a molecular link between the formation of these bodies, the ubiquitin protein degradation system, parkin and synphilin-1. (pages 1144−1150)
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-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease
