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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Medicine  7, 1102 - 1103 (2001) doi:10.1038/nm1001-1102 Turning WAT into BAT gets rid of fat Hubert C. Chen & Robert V. Farese Jr Gladstone Institute of Cardiovascular Disease and Cardiovascular Research Institute University of California, San Francisco California, USA hchen@gladstone.ucsf.edu or bfarese@gladstone.ucsf.edu Several knockout mouse models of leanness and obesity resistance have been reported over the past several years and have advanced our understanding of the pathogenesis and treatment of obesity. A new lean mouse model has been generated by inactivating the gene for an inhibitor of mRNA translation. (pages 1128−1131) MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REVIEWS OBESITY THERAPY: ALTERING THE ENERGY INTAKE-AND-EXPENDITURE BALANCE SHEET Nature Reviews Drug Discovery Review Article (01 Apr 2002)  See all 5 matches for Reviews RESEARCH Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1 Nature Medicine Article (01 Oct 2001) The major mRNA-associated protein YB-1 is a potent 5' cap-dependent mRNA stabilizer The EMBO Journal Article (01 Oct 2001) Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation The EMBO Journal Article (01 Aug 2001) Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20 The EMBO Journal Article (17 Aug 1998)  See all 8 matches for Research  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... Methods of Modeling Adaptation in Populations Deadline: Dec 30 2009 Reward: $15,000 USD The analysis of adaptation with a population is a frequently encountered computational modeling scen... More Challenges Powered by: nature jobs Tenure Track Assistant Professors Washington University School of Medicine St. Louis, MO 63110 United States Multiple Academic Positions in Psychology University of Toronto-Scarsborough Scarborough Ontario, Canada More science jobs Post a job for free Figures & Tables See also: Article by Tsukiyama-Kohara et al. Export citation Search buyers guide:   ADVERTISEMENT

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