NO vascular control in Duchenne muscular dystrophy
Rachelle H. Crosbie
Department of Physiological Science, University of California, Los Angeles, CA 90095
rcrosbie@physci.ucla.edu
A new investigation into Duchenne muscular dystrophy (DMD) pathogenesis suggests that at least part of the muscle degeneration observed in DMD patients may result from the reduced production of muscle membrane-associated neuronal nitric oxide synthase. This reduction may lead to impaired regulation of the vasoconstrictor response and eventual muscle damage.
