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| Editorial |  Top |
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Malaria: old challenge, new ideas p941
doi:10.1038/79590
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(62K)
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| Letters to Editor | Top |
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Re-evaluating sarcoplasmic reticulum function in heart failure pp942 - 943
Ulrike Delling, Mark A. Sussman
& Jeffery D. Molkentin
doi:10.1038/79592
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(153K)
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Reply to 'Re-evaluating sarcoplasmic reticulum function in heart failure' pp942 - 943
Kenneth R. Chien
doi:10.1038/79595
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(163K)
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| News | Top |
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Report suggests improvements to UK cancer research system... p945
Phyllida Brown
doi:10.1038/79597
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(132K)
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...and government responds p945
Karen Birmingham
doi:10.1038/79600
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(132K)
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ORI to study why cheaters cheat p946
Tinker Ready
doi:10.1038/79602
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(93K)
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Further trials stopped by OHRP pp946 - 947
Eric Niiler
doi:10.1038/79605
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(125K)
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US anticipates West Nile resurgence p947
Myrna E. Watanabe
doi:10.1038/79607
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(83K)
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Industry support for medical centers grows p948
Alan Dove
doi:10.1038/79610
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(91K)
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Folkman countersuit attacks "fraudulent" Abbott p948
Kristine Novak
doi:10.1038/79613
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(91K)
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Stowers Institute to open p949
Laura Bonetta
doi:10.1038/79615
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(87K)
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AIDS defined as unique military threat p949
Alan Dove
doi:10.1038/79618
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(87K)
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Transplant trials prove value of ITN p950
Tom Hollon
doi:10.1038/79620
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(59K)
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NIH funds gender biology research p950
Karen Birmingham
doi:10.1038/79622
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(59K)
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UK approves human stem cell research p950
Karen Birmingham
doi:10.1038/79624
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(59K)
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| Commentaries | Top |
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Design and construction of an experimental HIV-1 vaccine for a year-2000
clinical trial in Kenya. pp951 - 955
Tomas Hanke
& Andrew J. McMichael
doi:10.1038/79626
Abstract | Full text | PDF
(110K)
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Is the development of a new tuberculosis vaccine possible? pp955 - 960
Stefan H. E. Kaufmann
doi:10.1038/79631
Abstract | Full text | PDF
(342K)
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An issue of tissues: divining the split personalities of selective estrogen receptor modulators pp960 - 962
Neil J. McKenna
& Bert W. O'Malley
doi:10.1038/79637
Abstract | Full text | PDF
(148K)
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| Book Reviews | Top |
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Xeno: The Promise of Transplanting Animal Organs into Humans p963
Reviewed by: Jeffrey L. Platt
doi:10.1038/79640
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(116K)
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To America's Health: A Proposal to Reform the Food and Drug Administration pp963 - 964
Reviewed by: George Morstyn
doi:10.1038/79643
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(150K)
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| News and Views | Top |
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Molecular multitasking: statins lead to more arteries, less plaque pp965 - 966
Michael Simons
doi:10.1038/79646
Abstract | Full text | PDF
(78K)
See also: Article by Kureishi et al. |
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Designer cancer vaccines are still in fashion pp966 - 968
Arya Biragyn
& Larry W. Kwak
doi:10.1038/79649
Abstract | Full text | PDF
(164K)
See also: Article by Nair et al. |
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Listening for hoof beats in heart beats pp968 - 970
Jeffrey Robbins
& Gerald W Dorn II
doi:10.1038/79652
Abstract | Full text | PDF
(204K)
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How many factors are required to remodel bone? pp970 - 971
Gerard Karsenty
doi:10.1038/79655
Abstract | Full text | PDF
(181K)
See also: Article by Jochum et al. | Article by Sabatakos et al. |
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Pain, plasticity, and premature birth: a prescription for permanent suffering? pp971 - 973
K.J.S. Anand
doi:10.1038/79658
Abstract | Full text | PDF
(226K)
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Ibuprofen, inflammation and Alzheimer disease pp973 - 974
Tony Wyss-Coray
& Lennart Mucke
doi:10.1038/79661
Abstract | Full text | PDF
(73K)
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Combinations for cancer prevention pp974 - 975
Rajnish A. Gupta
& Raymond N. DuBois
doi:10.1038/79664
Abstract | Full text | PDF
(78K)
See also: Article by Torrance et al. |
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The impact of HIV on naïve T-cell homeostasis pp976 - 977
Zvi Grossman
& William E. Paul
doi:10.1038/79667
Abstract | Full text | PDF
(107K)
See also: Article by Hazenberg et al. |
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Lipid biochemistry takes a stand against tuberculosis pp977 - 978
Philip Draper
doi:10.1038/79670
Abstract | Full text | PDF
(78K)
See also: Article by Zimhony et al. |
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Research News p979
Kristine Novak, John MacFarlane
& Kimberly Gavin
doi:10.1038/79673
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(84K)
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| Articles | Top |
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Increased bone formation and osteosclerosis in mice overexpressing the
transcription factor Fra-1 pp980 - 984
Wolfram Jochum, Jean-Pierre David, Candace Elliott, Anton Wutz, Hanns Plenk Jr., Koichi Matsuo
& Erwin F. Wagner
doi:10.1038/79676
Abstract | Full text | PDF
(1,011K)
See also: News and Views by Karsenty |
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Overexpression of  FosB transcription factor(s) increases bone
formation and inhibits adipogenesis pp985 - 990
G. Sabatakos, N. A. Sims, J. Chen, K. Aoki, M. B. Kelz, M. Amling, Y. Bouali, K. Mukhopadhyay, K. Ford, E. J. Nestler
& R. Baron
doi:10.1038/79683
Abstract | Full text | PDF
(884K)
See also: News and Views by Karsenty |
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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains pp991 - 997
Christelle Peyron, Juliette Faraco, William Rogers, Beth Ripley, Sebastiaan Overeem, Yves Charnay, Sona Nevsimalova, Michael Aldrich, David Reynolds, Roger Albin, Robin Li, Marcel Hungs, Mario Pedrazzoli, Muralidhara Padigaru, Melanie Kucherlapati, Jun Fan, Richard Maki, Gert Jan Lammers, Constantin Bouras, Raju Kucherlapati, Seiji Nishino
& Emmanuel Mignot
doi:10.1038/79690
Abstract | Full text | PDF
(430K)
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Metformin reverses fatty liver disease in obese, leptin-deficient mice pp998 - 1003
Hui Zhi Lin, Shi Qi Yang, Christine Chuckaree, Francis Kuhajda, Gabriele Ronnet
& Anna Mae Diehl
doi:10.1038/79697
Abstract | Full text | PDF
(288K)
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The HMG-CoA reductase inhibitor simvastatin activates the protein kinase
Akt and promotes angiogenesis in normocholesterolemic animals. pp1004 - 1010
Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima, Ann Bialik, David Fulton, David J. Lefer, William C. Sessa
& Kenneth Walsh
doi:10.1038/79510
Abstract | Full text | PDF
(372K)
See also: News and Views by Simons |
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Induction of cytotoxic T cell responses and tumor immunity against unrelated
tumors using telomerase reverse transcriptase RNA transfected dendritic cells.
pp1011 - 1017
Smita K. Nair, Axel Heiser, David Boczkowski, Anish Majumdar, Michio Naoe, Jane S. Lebkowski, Johannes Vieweg
& Eli Gilboa
doi:10.1038/79519
Abstract | Full text | PDF
(126K)
See also: News and Views by Biragyn & Kwak |
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Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia pp1018 - 1023
Jeffrey J. Molldrem, Peter P. Lee, Changqing Wang, Kyrie Felio, Hagop M. Kantarjian, Richard E. Champlin
& Mark M. Davis
doi:10.1038/79526
Abstract | Full text | PDF
(126K)
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Combinatorial chemoprevention of intestinal neoplasia pp1024 - 1028
Christopher J. Torrance, Peta E. Jackson, Elizabeth Montgomery, Kenneth W. Kinzler, Bert Vogelstein, Allan Wissner, Maria Nunes, Philip Frost
& Carolyn M. Discafani
doi:10.1038/79534
Abstract | Full text | PDF
(392K)
See also: News and Views by Gupta & DuBois |
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Genetic analysis of chemoresistance in primary murine lymphomas pp1029 - 1035
Clemens A. Schmitt, Christine T. Rosenthal
& Scott W. Lowe
doi:10.1038/79542
Abstract | Full text | PDF
(573K)
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Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection pp1036 - 1042
Mette D. Hazenberg, Sigrid A. Otto, James W.T. Cohen Stuart, Martie C.M. Verschuren, Jan C.C. Borleffs, Charles A.B. Boucher, Roel A. Coutinho, Joep M.A. Lange, Tobias F. Rinke de Wit, Aster Tsegaye, Jacques J.M. van Dongen, Dörte Hamann, Rob J. de Boer
& Frank Miedema
doi:10.1038/79549
Abstract | Full text | PDF
(138K)
See also: News and Views by Grossman & Paul |
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Pyrazinamide inhibits the eukaryotic-like fatty acid synthetase I (FASI) of Mycobacterium tuberculosis pp1043 - 1047
Oren Zimhony, Jeffery S. Cox, John T. Welch, Catherine Vilchèze
& William R. Jacobs Jr.
doi:10.1038/79558
Abstract | Full text | PDF
(116K)
See also: News and Views by Draper |
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Galanin-1 receptor up-regulation mediates the excess colonic fluid production caused by infection with enteric pathogens pp1048 - 1051
Kristina A. Matkowskyj, Alexey Danilkovich, Jorge Marrero, Suzana D. Savkovic, Gail Hecht
& Richard V. Benya
doi:10.1038/79563
Abstract | Full text | PDF
(266K)
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| New Technology | Top |
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A new method for screening anti-infective biomaterials pp1053 - 1056
Thorsten Bechert, Peter Steinrücke
& Josef-Peter Guggenbichler
doi:10.1038/79568
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(679K)
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In situ detection of virus- and tumor-specific T-cell immunity pp1056 - 1060
John B.A.G. Haanen, Monique G.C.T. van Oijen, Felicia Tirion, Lauran C.J.M. Oomen, Ada M. Kruisbeek, Florry A. Vyth-Dreese
& Ton N.M. Schumacher
doi:10.1038/79573
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(1,216K)
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On the market pp1060 - 1061
doi:10.1038/79580
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(177K)
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| Erratum | Top |
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Errata p1062
doi:10.1038/79586
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(90K)
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