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Molecular multitasking: statins lead to more arteries, less plaque

Statins, commonly prescribed cholesterol-lowering drugs, have also been identified as anti-oxidants, anti-inflammatories and now, as angiogenic agents. Elucidation of the statin signal transduction pathway should reveal how one class of drugs can have so many activities (pages 1004–1010).

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Figure 1: Simvastatin, Akt signaling and angiogenesis.

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Simons, M. Molecular multitasking: statins lead to more arteries, less plaque. Nat Med 6, 965–966 (2000). https://doi.org/10.1038/79646

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