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Nature Medicine  6, 974 - 975 (2000)
doi:10.1038/79664

Combinations for cancer prevention

Rajnish A. Gupta & Raymond N. DuBois

Departments of Medicine and Cell Biology, Vanderbilt University Medical Center, The Vanderbilt-Ingram Cancer Center, Nashville Veterans Affairs Medical Center, Nashville, Tennessee 37232-2279
duboisrn@ctrvax.vanderbilt.edu

Combination therapies involving inhibitors of the epidermal growth factor and cyclooxygenase signaling prevent colorectal adenomas in mice. This synergistic effect may be due to the convergance of these two signaling pathways (pages 1024−1028).

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Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X
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