Departments of Medicine and Cell Biology, Vanderbilt
University Medical Center, The Vanderbilt-Ingram Cancer Center, Nashville
Veterans Affairs Medical Center, Nashville, Tennessee
37232-2279
duboisrn@ctrvax.vanderbilt.edu
Combination therapies involving inhibitors of the epidermal growth
factor and cyclooxygenase signaling prevent colorectal adenomas in mice. This
synergistic effect may be due to the convergance of these two signaling pathways
(pages 1024−1028).