1
Division of Molecular Cardiovascular Biology Children's Hospital Research Foundation, 3333 Burnet Avenue Cincinnati, Ohio 45229-3039
jeff.robbins@chmcc.org
2
Division of Cardiology University of Cincinnati 231 Bethesda Avenue Cincinnati, Ohio, 45267-0542
dorngw@ucmail.uc.edu
Disruption of the Sp1-related transcription factor HF-1b leads to alterations in the cardiac conduction system that result in ventricular arrhythmias and sudden death. What does this tell us about how ventricular cardiomyocytes differentiate into the specialized cells that form the heart's conductance system?