Transcriptional regulation of cellular transformation
Paolo Salomoni
& Pier Paolo Pandolfi
Department of Human Genetics and Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Division, Graduate School of Medical Sciences, Cornell University, 1275 York Avenue, New York, NY 10021, USA
p-pandolfi@ski.mskcc.org
Structurally and functionally altered transcription factors have been associated with many human neoplasms. A better understanding of these transcriptional defects has revealed new therapeutic opportunities.