Aaron Diamond AIDS Research Center The Rockefeller
University 455 First Avenue New York,
New York 10016, USA dho@adarc.org
In patients with human immunodeficiency virus 1, a comparison of
the genotype of rebounding virus to that in the latent reservoir after highly
active anti-retroviral therapy is discontinued indicates that the latent reservoir
is not the cause of viral rebound in most cases. However, the precise anatomic
location of the source of viral rebound is still undefined (pages
757−761).