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Nature Medicine 6, 711 - 714 (2000)
doi:10.1038/76299

Assessing tumors in living animals through measurement of urinary bold beta-human chorionic gonadotropin

Ie-Ming Shih1,2, Christopher Torrance1, Lori J. Sokoll2, Daniel W. Chan1,2, Kenneth W. Kinzler1 & Bert Vogelstein1,3

  1. The Johns Hopkins Oncology Center, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
  2. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
  3. Howard Hughes Medical Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA

Correspondence to: Bert Vogelstein1,3 e-mail: vogelbe@welchlink.welch.jhu.edu

There is no tool more essential to cancer research than the experimental tumor. Every therapeutic and preventative strategy uses such tumors, and tumors growing in animals are instrumental for basic studies of cancer biology1, 2, 3.

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