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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications Review Nature Medicine  6, 513 - 519 (2000) doi:10.1038/74994 Mitochondrial control of cell death Guido Kroemer1 & John C. Reed2 1  Centre National de la Recherche Scientifique, CNRS-ULR1599, Institut Gustave Roussy 24 rue Calmette Desmoulins, F-94805 Villejuif kroemer@infobiogen.fr 2  The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037 USA jreed@burnham.org In many instances, permeabilization of mitochondrial membranes is a rate-limiting step of apoptotic or necrotic cell demise. This has important consequences for the pathophysiology of cell death, as well as for its pharmacological control.  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Optimizing Sub-cellular Localization Tags Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression.... Methods of Modeling Adaptation in Populations Deadline: Dec 30 2009 Reward: $15,000 USD The analysis of adaptation with a population is a frequently encountered computational modeling scen... More Challenges Powered by: nature jobs Tenure Professor for Bone and Skeleton Research Westfalian Wilhelms-University Munster, Germany Munster Germany Multiple Academic Positions in Psychology University of Toronto-Scarsborough Scarborough Ontario, Canada More science jobs Post a job for free Figures & Tables Export citation Search buyers guide:   ADVERTISEMENT

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